Mathematics, Vol. 11, Pages 4541: A Mechanistic Model for Long COVID Dynamics

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Mathematics, Vol. 11, Pages 4541: A Mechanistic Model for Long COVID Dynamics

Mathematics doi: 10.3390/math11214541

Authors: Jacob Derrick Ben Patterson Jie Bai Jin Wang

Long COVID, a long-lasting disorder following an acute infection of COVID-19, represents a significant public health burden at present. In this paper, we propose a new mechanistic model based on differential equations to investigate the population dynamics of long COVID. By connecting long COVID with acute infection at the population level, our modeling framework emphasizes the interplay between COVID-19 transmission, vaccination, and long COVID dynamics. We conducted a detailed mathematical analysis of the model. We also validated the model using numerical simulation with real data from the US state of Tennessee and the UK.

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