Molecules, Vol. 29, Pages 1856: Exploring the Pharmacological Potential of Lithospermum officinale L.: A Review of Phytochemicals and Ethnomedicinal Uses

Molecules, Vol. 29, Pages 1856: Exploring the Pharmacological Potential of Lithospermum officinale L.: A Review of Phytochemicals and Ethnomedicinal Uses

Molecules doi: 10.3390/molecules29081856

Authors: Gulzhanat Barkizatova Aknur Turgumbayeva Kairat Zhakipbekov Kuralay Bekesheva Zhalgaskali Arystanov Tanagul Arystanova Farida Kayupova Klara Zhumalina Zhanat Toxanbayeva Aigul Ibragimova Olga Blinova Gulnara Utegenova Nurzhan Iztileu Zhanserik Shynykul

Exploring phytochemicals from ethnomedicinal plants for pharmacological applications is a promising research area. By studying ethnomedicine, researchers can identify plants used for centuries to treat ailments and investigate their phytochemicals. Consequently, phytochemicals can be isolated, characterized, and tested for pharmacological activities, leading to new drug development. This research also helps preserve traditional knowledge and biodiversity. Lithospermum officinale L., found in Eurasia, Argentina (South), Colombia, and the United States, is valued for its medicinal properties, including anti-inflammatory, antioxidant, and antimicrobial effects. The current review emphasizes L. officinale L. as a significant reservoir of bioactive phytochemicals, with alkaloids, quinones, glucosides, phenolics, flavonoids, and lipids identified as the principal metabolites. It also unveils the unexplored potential of this plant for future research endeavors. Continued research on L. officinale L. can unlock its full potential, providing insights into its medicinal uses and contributing to biodiversity preservation.