Nutritional supplements for migraine prevention: evaluating evidence sufficiency and effect modifiers through network meta-analysis, trial sequential analysis, and meta-regression

BackgroundThis network meta-analysis (NMA) integrated trial sequential analysis (TSA) limited to eligible direct pairwise comparisons and network meta-regression to compare efficacy and safety of nutritional supplements for migraine prevention, assess evidence maturity and identify potential effect modifiers.MethodsWe retrieved randomized controlled trials (RCTs) of nutritional supplements for ...